|
T1409 |
Methocarbamol
|
Lumirelax,Metocarbamol,AHR 85,Robaxin |
Sodium Channel
,
Carbonic Anhydrase
|
|
Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful musc... |
|
T0992 |
Carbenoxolone disodium
|
Biogastrone,Duogastrone,Bioral |
Gap Junction Protein
|
|
Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, ... |
|
T1594 |
Vecuronium bromide
|
ORG NC 45 |
AChR
|
|
Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle relaxant activity. |
|
T1072 |
Loxeen
|
Pridinol methanesulfonate |
AChR
|
|
Loxeen (Pridinol methanesulfonate) is used as an anticholinergic and as an antiparkinsonian agent. |
|
T8815 |
Azumolene
|
EU4093 free base |
Calcium Channel
|
|
Azumolene (EU4093 free base) |
|
T22371 |
Mivacurium dichloride
|
Mivacurium chloride |
AChR
|
|
Mivacurium dichloride (Mivacurium chloride) is a non-depolarising, rapid neuromuscular blocker of short duration, used therefore as anesthetic, to provide skeletal muscle relaxation in minor surgical operations, in emerg... |
|
T4993 |
Afloqualone
|
HQ-495 |
GABA Receptor
|
|
Afloqualone (HQ-495) is a agonist of GABA Receptor . Target: GABA Receptor in vitro: Afloqualone is a quinazolinone family GABAergic drug. It has sedative and muscle-relaxant effects, resulting from its agonist activity ... |
|
T7843 |
4-phenoxypiperidine
|
|
Others
|
|
4-phenoxypiperidines with muscle relaxant and anticonvulsant activities. |
|
T1650 |
Chlorzoxazone
|
Paraflex,Chlorzoxazon |
P450
,
Potassium Channel
|
|
Chlorzoxazone (Chlorzoxazon) is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of Centrally-mediated Muscle Relaxation. |
|
T0015 |
Mephenesin
|
Cresoxydiol,Memphenesin,Mephedan,Decontractyl |
NMDAR
,
iGluR
|
|
Mephenesin (Cresoxydiol) is a centrally acting muscle relaxant with a short duration of action. |
|
T1459 |
Cisatracurium besylate
|
51W89 |
Adrenergic Receptor
,
AChR
,
Autophagy
|
|
Cisatracurium besylate (51W89) is a nondepolarizing skeletal muscle relaxant for intravenous administration. |
|
T0922 |
Zoxazolamine
|
NSC 24995,Contrazole |
Others
|
|
Zoxazolamine (NSC-24995) is a uricosuric and muscle relaxant. Zoxazolamine acts centrally as a muscle relaxant, but the mechanism of its action is not understood. |
|
T6618 |
Orphenadrine Citrate
|
Flexon,Flexoject,Banflex |
AChR
,
iGluR
|
|
Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects. |
|
T10893 |
CS-722 Free base
|
|
Others
|
|
CS-722 Free base is a synthetic central muscle relaxant with muscle relaxant activity and inhibitory effect on spinal reflex. CS-722 Free base may inhibit spontaneous inhibitory post-synaptic current and excitatory post-... |
|
T1509 |
Cyclobenzaprine hydrochloride
|
Cyclobenzaprine HCl,MK130 hydrochloride |
5-HT Receptor
|
|
Cyclobenzaprine hydrochloride (MK130 hydrochloride) , a centrally acting muscle relaxant with antidepressant activity, leads to a reduction in muscle spasms. |
|
T0504 |
Cyclandelate
|
BS 572,3,5,5-Trimethylcyclohexyl mandelate |
Acyltransferase
|
|
Cyclandelate (BS 572), a direct-acting smooth muscle relaxant, is used to dilate blood vessels. |
|
T7338 |
DHBP dibromide
|
Diheptylviologen dibromide,1,1'-DI-N-HEPTYL-4,4'-BIPYRIDINIUM DIBRO |
Calcium Channel
|
|
DHBP dibromide (1,1'-DI-N-HEPTYL-4,4'-BIPYRIDINIUM DIBRO) is calcium release and a muscle relaxant inhibitor. |
|
T1864 |
Fabomotizole
|
Obenoxazine,CM346 |
Others
|
|
Fabomotizole (Obenoxazine) is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. |
|
T0563 |
Homoveratronitrile
|
|
Others
|
|
Homoveratronitrile is an impurity of Verapamil. It is also an intermediate in the preparation of the muscle relaxant Papverine. |
|
T64851 |
Phenprobamate
|
MH 532,Proformiphen,3-Phenylpropyl carbamate |
|
|
Phenprobamate (MH 532) is a relaxant that acts on central skeletal muscle and has anticonvulsant and psychostimulant effects. |
|
T1610 |
Metaxalone
|
Skelaxin,Methaxalonum,Zorane,NSC170959,AHR438 |
Others
|
|
Metaxalone (Methaxalonum) (marketed by King Pharmaceuticals under the brand name Skelaxin ) is a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions. |
|
T0156 |
Rocuronium bromide
|
ORG 9426,ORG 9426 (Bromide) |
AChR
|
|
Rocuronium bromide (ORG 9426) is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker. During surgery or mechanical ventilation, it is used to facilitate endotracheal intubation and to provide skeleta... |
|
T4054 |
Dantrolene sodium hemiheptahydrate
|
Dantrolene sodium hydrate,Dantrolene sodium salt,Dantrium,Sodium dantrolene |
Calcium Channel
,
Autophagy
|
|
Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium concentration. Ryanodine receptors mediate the release of calcium from t... |
|
T68087 |
Inaperisone
|
|
Others
|
|
Inaperisone is a novel centrally acting muscle relaxant that inhibits the voiding reflex. Inaperisone may inhibit the voiding reflex by acting indirectly on GABAB receptors in the brainstem. |
|
T0077 |
Dantrolene sodium
|
Lapatinib ditosylate monohydrate,Dantrolene sodium salt |
Others
,
Calcium Channel
|
|
Dantrolene sodium (Lapatinib ditosylate monohydrate) salt is a skeletal muscle relaxant and can interfere with excitation-contraction coupling in the muscle fiber. It is used for the treatment of spasticity and other neu... |
|
T28972 |
Tiaramide hydrochloride
|
FK-1160,NTA-194,FK 1160,FK1160,tiaramide |
Others
|
|
Tiaramide hydrochloride (FK-1160) is an anti-inflammatory drug that inhibits the action of mediators released from mast cells and has direct smooth muscle relaxant properties. |
|
T0511 |
Tolperisone hydrochloride
|
Muscalm,Midocalm,Tolperisone HCl |
Sodium Channel
|
|
Tolperisone hydrochloride (Muscalm), a centrally acting muscle relaxant, is used in the therapy of pathologically increased tone of the cross-striated muscle resulted by neurological diseases (damage of the encephalomyel... |
|
T28778 |
Silperisone HCl
|
RGH5002,SILA336,RGH-5002,Silperisone hydrochloride,SILA-336 |
|
|
Silperisone HCl (RGH-5002) blocks sodium and calcium channels in cells, decreases excitability and contractility of muscle cells, reduces peripheral tone, and acts as a muscle relaxant and peripheral vasodilator. Silperi... |
|
T8452 |
Dantrolene
|
|
Others
|
|
Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors. |
|
T5005 |
Eperisone hydrochloride
|
|
Others
|
|
Eperisone is a skeletal muscle relaxant and a spasmolytic agent related structurally to Tolperisone. |
|
T1475 |
Fesoterodine fumarate
|
Toviaz,SPM 907 |
AChR
|
|
Fesoterodine fumarate (Toviaz) is the fumarate salt form of fesoterodine, a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. Fesoterodine is rapidly hydrolyzed in vivo... |
|
T0166 |
Pancuronium dibromide
|
Pancuronium bromide,Pavulon |
AChR
|
|
Pancuronium dibromide (Pavulon), a competitive AChR antagonist (IC50 = 5.5 nM), acts as a skeletal muscle relaxant. Pancuronium dibromide(Pancuronium bromide) blocking neuromuscular transmission is achieved by competing ... |
|
T71356 |
Lanperisone HCl
|
|
|
|
Lanperisone, also known as NK433, is a muscle relaxant. NK433 inhibited the facilitation of the flexor reflex mediated by group II afferent fibers that was induced by intrathecal administration of noradrenaline-HCl. NK43... |
|
T16344 |
NS-2028
|
|
Others
,
Guanylate cyclase
|
|
NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor (IC50: 30 nM and 200 nM for basal and NO-stimulated enzyme activity). It is commonly used in the research of nitric oxide signaling pathways. NS-2028... |
|
T32561 |
Lanperisone
|
|
|
|
Lanperisone is a muscle relaxant. |
|
T25236 |
Chinotilin
|
Quinotiline,Khinotilin |
|
|
Chinotilin is a muscle relaxant antagonist. |
|
T29950 |
Ambenoxan
|
Ambenoxanum |
|
|
Ambenoxan is a centrally acting muscle relaxant. |
|
T21050 |
Pridinol
|
|
|
|
Pridinol is an antispasmodic and muscle relaxant. |
|
T31105 |
CS 722
|
CS-722,CS722 |
|
|
CS 722 is a centrally acting muscle relaxant. CS-722 exerts its muscle relaxant action by affecting both the supraspinal structure and the spinal cord. |
|
T31130 |
Cyclarbamate
|
C-1428,Ciclarbamato,C 1428,Cyclarbamatum |
|
|
Cyclarbamate is a muscle relaxant and a sedative. |
|
T15591 |
Ipenoxazone
|
NC-1200,MLV-6976 |
Others
|
|
Ipenoxazone is an effective and centrally acting muscle relaxant. |
|
T29950L |
Ambenoxan hydrochloride
|
Ambenoxan HCl |
|
|
Ambenoxan hydrochloride is a centrally acting skeletal muscle relaxant. |
|
T32406 |
KMUP-4
|
KMUP 4 |
|
|
Kmup-4 is an enhancer of cGMP activity and an aortic smooth muscle relaxant. |
|
T27585 |
Idrocilamide
|
Brolitene |
|
|
Idrocilamide exhibits muscle relaxant and anti-inflammatory properties. |
|
T33936 |
Perimetazine
|
RP 9159,RP-9159,AN1317,AN-1317,AN 1317 |
|
|
Perimetazine has effects on central nervous system depressent such as sedative and muscle relaxant effects. |
|
T32405 |
KMUP-3
|
KMUP 3,KMUP3 |
|
|
KMUP-3 is an enhancer of cGMP activity, and acts as an aortic smooth muscle relaxant. |
|
T30196 |
Atherospermidine
|
|
|
|
Atherospermidine is a smooth muscle relaxant aporphines from Artabotrys maingayi. |
|
T24057 |
Fazadinium bromide
|
|
|
|
Fazadinium bromide is a muscle relaxant. It acts as a nicotinic acetylcholine receptor antagonist through the neuromuscular blockade. |
|
T30171 |
Aspaminol
|
|
|
|
Aspaminol is a smooth muscle relaxant. |
|
T29752 |
AHR-2666
|
AHR 2666 |
|
|
AHR-2666 is a skeletal muscle relaxant. |
